Hoffmann M*,  Wong L-YR *, Arora P*, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. 2023. Omicron subvariant BA.5 efficiently infects lung cells. 1. Nat Commun 14:3500.

Wong L-YR, Perlman S. 2023. Proviral role of caspase-6 in coronavirus infections. 1. Cell Res 33:7–8.

El-Kafrawy, S.A., Odle, A., Abbas, A.T., Hassan, A.M.., Abdel-Dayem, U.A., Qureshi, A.K., Wong, L.-Y.R., Zheng, J., Meyerholz, D.K., Perlman, S., Zumla, A., Azhar, EI. (2022). SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. PLoS Pathogen 18, (9):e1010782. doi: 10.1371/journal.ppat.1010782.

Kibler, K.V., Szczerba, M., Lake, D., Roeder, A.J., Rahman, M., Hogue, B.G., Wong, L.-Y.R., Perlman, S., Li, Y., and Jacobs, B.L. (2022). Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2. Vaccines 10, 1172. https://doi.org/10.3390/vaccines10081172.

Wong, L.-Y.R., Zheng, J., Wilhelmsen, K., Li, K., Ortiz, M.E., Schnicker, N.J., Thurman, A., Pezzulo, A.A., Szachowicz, P.J., Li, P., et al. (2022). Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19. Nature 605, 146–151. https://doi.org/10.1038/s41586-022-04630-3.

Halfmann, P.J., Iida, S., Iwatsuki-Horimoto, K., Maemura, T., Kiso, M., Scheaffer, S.M., Darling, T.L., Joshi, A., Loeber, S., Singh, G.,…..Wong, L.-Y.R,….et al. (2022). SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters. Nature 603, 687–692. https://doi.org/10.1038/s41586-022-04441-6.

Wong, L.-Y.R., and Perlman, S. (2021). Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy? Nat. Rev. Immunol. 1–10.

Dampalla, C.S., Zheng, J., Perera, K.D., Wong, L.-Y.R., Meyerholz, D.K., Nguyen, H.N., Kashipathy, M.M., Battaile, K.P., Lovell, S., Kim, Y., et al. (2021). Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proc. Natl. Acad. Sci. U. S. A. 118, e2101555118.

Wong, L.-Y.R., Zheng, J., Sariol, A., Lowery, S., Meyerholz, D.K., Gallagher, T., and Perlman, S. (2021). Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence. Proc. Natl. Acad. Sci. U. S. A. 118, e2102983118.

Zheng, J., Meyerholz, D., Wong, L.-Y.R., Gelb, M., Murakami, M., and Perlman, S. (2021). Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. J. Clin. Invest. 131, 147201.

Zheng, J.*, Wong, L.-Y.R.*, Li, K.*, Verma, A.K.*, Ortiz, M.E., Wohlford-Lenane, C., Leidinger, M.R., Knudson, C.M., Meyerholz, D.K., McCray, P.B., et al. (2021). COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature 589, 603–607.

Zhu, L., Fung, S.-Y., Xie, G., Wong, L.-Y.R., Jin, D.-Y., and Cai, Z. (2020). Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab. Mol. Cell. Proteomics MCP 19, 1303–1309. 

Wong, L.-Y.R., Li, K., Sun, J., Zhuang, Z., Zhao, J., McCray, P.B., and Perlman, S. (2020). Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2. STAR Protoc. 1, 100169. 

Wong, L.-Y.R.*, Ye, Z.-W.*, Lui, P.-Y., Zheng, X., Yuan, S., Zhu, L., Fung, S.-Y., Yuen, K.-S., Siu, K.-L., Yeung, M.-L., et al. (2020). Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε. J. Immunol. 205, 1564–1579.

Sun, J.*, Zhuang, Z.*, Zheng, J.*, Li, K.*, Wong, R.L.-Y.*, Liu, D.*, Huang, J.*, He, J.*, Zhu, A., Zhao, J.*, et al. (2020). Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell 182, 734-743.e5.

Lui, P.-Y.*, Wong, L.-Y.R.*, Ho, T.-H., Au, S.W.N., Chan, C.-P., Kok, K.-H., and Jin, D.-Y. (2017). PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization. J. Immunol. Baltim. Md 1950 199, 1846–1855.

Lui, P.-Y.*, Wong, L.-Y.R.*, Fung, C.-L., Siu, K.-L., Yeung, M.-L., Yuen, K.-S., Chan, C.-P., Woo, P.C.-Y., Yuen, K.-Y., and Jin, D.-Y. (2016). Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. Emerg. Microbes Infect. 5, e39.

Wong, L.-Y.R., Lui, P.-Y., and Jin, D.-Y. (2016). A molecular arms race between host innate antiviral response and emerging human coronaviruses. Virol. Sin. 31, 12–23.

*Denotes co-first authors